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Ensure the safety and efficacy of your biologics with our downstream protein refolding CDMO solutions.
Downstream protein refolding helps to ensure the correct folding and assembly of biologics, which is essential for the safety, efficacy and stability of the final product. Once biologics have been purified and refolded, they can be purified again to remove any impurities or aggregates generated during refolding. The purified biologic is then ready for formulation steps.
Proper protein refolding prevents the formation of aggregates and other misfolded species, which can lead to immunogenicity, reduced potency and other adverse effects. Optimizing refolding conditions is a complex process that requires a deep understanding of the protein’s structure and stability.
What modalities can we handle with our downstream protein refolding?
With our downstream protein refolding methods we can ensure that your biologics are correctly folded and assembled, optimizing their therapeutic effects.
We are a global CDMO and biosimilar developer dedicated to impacting the global healthcare landscape by bringing trusted and affordable medicines to market, quickly.
Committed to innovation, we have revolutionized biologics production with our patented and validated continuous bioprocess manufacturing platform, EnzeneX™, that enables us to significantly reduce the cost of producing complex biologics and monoclonal antibodies (mAbs).
Our fully-integrated services and productive pipeline of biosimilars, along with our downstream refolding methods, are designed to cater to your project’s every need.
Fueled by our continuous innovation and armed with EnzeneX™, our fully-integrated CDMO solutions and our biosimilars pipeline are designed to help bring your biologics innovations to life.