Cell line engineering
Kickstart your biologics development journey with our highly-expressing mammalian and microbial cell lines.
What is cell line engineering?
The first step in biologics development, cell line engineering involves the manipulation of mammalian or microbial cell lines to express a desired therapeutic.
Our cell line engineering solutions can help to improve the quality, cost-effectiveness and yield of your biologics products.
Understanding our cell line engineering solutions
What can we offer you?
- Proprietary CHO cell lines
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- CHO-K1, CHO GS -/- and CHO DHFR -/- cells for high expression in fed-batch and perfusion processes
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- Highly-expressing E. coli cell lines
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- Bacterial expression platform E. coli BL21 and plasmid DNA platform E. coli DH5α
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- Clonal expression vectors and selection
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- Commercial and proprietary vectors for antibiotic, GS (glutamine synthetase) and DHFR (dihydrofolate reductase) selection
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Optimize your product expression
Optimize your product expression After engineering your chosen cell line to express your gene of interest (GOI), clone, screen and optimize production with our cell line development solutions.
Safeguard your product development
Collect, characterize and store your engineered cell lines and safeguard your product development with our cell banking solutions.
Why partner with Enzene for cell line engineering?
We are a global CDMO and biosimilar developer dedicated to impacting the global healthcare landscape by bringing trusted and affordable medicines to market, quickly.
Committed to innovation, we have revolutionized biologics production with our patented and validated continuous bioprocess manufacturing platform, EnzeneX™, that enables us to significantly reduce the cost of producing complex biologics and monoclonal antibodies (mAbs).
Our fully-integrated services and productive pipeline of biosimilars, along with our cell line engineering solutions, are designed to cater to your project’s every need.
Related case studies
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Join the revolution
Fueled by our continuous innovation and armed with EnzeneX™, our fully-integrated CDMO solutions and our biosimilars pipeline are designed to help bring your biologics innovations to life.