Upstream process development

Increase yields and reduce costs with our innovative upstream process development CDMO solutions. 

What is upstream process development?

Once cell lines have been engineered and optimized, cell culture begins as part of upstream process development. Cells are cultured in bioreactors to produce the biologic of interest. Our upstream process development services include fed-batch cultures or continuous perfusion approaches.

What modalities can we handle with our upstream process development?

  • Monoclonal antibodies (mAbs)
  • Therapeutic recombinant proteins
  • Recombinant enzymes
  • Conjugated proteins
  • Bispecific proteins
  • Fusion proteins
  • Plasmid DNA (pDNA)

 

Discover continuous upstream processing

Processing that continues without interruption. We use single-use bioreactors and intensified perfusion to achieve continuous upstream processing and bring you:

  • High-quality and efficient processing
  • Cost-effective manufacturing
  • Flexibility to scale-on and scale-out

We offer continuous processing as part of our upstream process development or our patented and fully-validated continuous bioprocess manufacturing platform, EnzeneX™.

Why partner with Enzene for upstream process development?

We are a global CDMO and biosimilar developer dedicated to impacting the global healthcare landscape by bringing trusted and affordable medicines to market, quickly.

Committed to innovation, we have revolutionized biologics production with our patented and validated continuous bioprocess manufacturing platform, EnzeneX™, that enables us to significantly reduce the cost of producing complex biologics and monoclonal antibodies (mAbs).

Our fully-integrated services and productive pipeline of biosimilars, along with our upstream process development solutions, are designed to cater to your project’s every need.

Join the CDMO revolution

Fueled by our continuous innovation and armed with EnzeneX™, our fully-integrated CDMO solutions and our biosimilars pipeline are designed to help bring your biologics innovations to life.