Plasmid DNA
Optimize your plasmid DNA (pDNA) production for efficient and effective therapeutic use with our development and manufacturing solutions.
Why develop pDNA?
Plasmid DNA is used as a therapeutic in various ways, including:
- Viral vectors for gene therapies: pDNA can be engineered to carry specific genetic material, such as genes encoding therapeutic proteins, into cells. Delivered to target cells using a viral vector, the therapeutic gene is expressed and the desired therapeutic response is facilitated
- DNA vaccination: pDNA encoding antigens (e.g., viral proteins) can be directly administered as a vaccine. The pDNA is taken up by cells and the encoded antigen is expressed. This elicits an immune response, generating antibodies and T cells specific to the antigen
Advantages including versatility, efficiency, scalability and specificity make pDNA a critical tool for the treatment of a diverse range of therapeutic indications.
Understanding our pDNA production
Our experience, expertise, and state-of-the-art facilities can deliver high-quality pDNA in high yields ready for your therapeutic application. Used in combination with our AAVENZENE kit, recombinant adeno-associated virus (rAAV) particles that specifically deliver DNA to target cells can be produced. For this kit, custom-designed research-grade plasmids can be tailored to suit any gene of interest.
Why partner with Enzene for your pDNA?
We are a global CDMO and biosimilar developer dedicated to impacting the global healthcare landscape by bringing trusted and affordable medicines to market, quickly.
We understand that each modality has unique requirements, and we are committed to providing you with the highest quality products and services. Our flexible development and manufacturing platforms allow us to quickly and efficiently produce modalities, regardless of their complexity or scale.
Our proprietary continuous bioprocess manufacturing platform, EnzeneX™ further enhances production, with accelerated rates and a significant reduction in the cost of producing complex modalities — from mAbs to complex proteins.
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A modality for every need
Fueled by our continuous innovation and armed with our wide variety of modalities, we are dedicated to bringing your biologics innovations to life.