Synthetic peptides

Why develop synthetic peptides?

Peptides offer several advantages as therapeutic molecules and have shown promise as treatments for complex disease indications. Their advantages include high specificity leading to reduced off-target effects, increased efficacy and low immunogenicity.

Understanding our synthetic peptide production

We offer a range of peptide synthesis services tailored to meet your requirements. Our peptide synthesis platform can help to navigate your peptide synthesis, with extensive experience in the development and manufacturing of peptide products from milligram to multigram scale. We can provide:

• In-depth scientific knowledge and understanding of solid, solution and hybrid phase peptide synthesis
• Process development and manufacturing for both solution and solid-phase peptide synthesis
• The design of scalable peptide syntheses through solid and solution phase synthesis
• Development of long-chain peptides (up to 40 amino acids), modified peptides, cyclic peptides and disulfide-bridged peptides
• Expertise in post-translational modifications like PEGylation, biotinylation, acetylation and amidation
• Purification method development using preparative HPLC
• Large-scale lyophilization of pure peptides
• Scale-up and tech transfer for gram-scale manufacturing
• GMP peptide manufacture to support clinical programs through the drug development pipeline

Our synthetic peptide facilities

Our state-of-the-art facilities are ready for your peptide synthesis project, including:

• Fully automated peptide synthesizer (CS Bio) of 200L capacity
• Manual peptide synthesis reactor 100ml to 20L
• Preparative HPLC (Hanbon flow 600 mL/min and 3.0 L/min, Waters flow 300L/min and YMC flow 8.0L/min)
• RP-HPLC purification columns of 20mm, 80mm, 100mm and 450mm sizes
• Lyophilizer (6 kg and 100 kg condenser capacity)
• Storage facility at 2-8^oC for amino acids and reagents
• Storage facility at 20^oC for purified peptide
• Nanofiltration unit of (5L and 100L capacity)