We have launched several biosimilar products by leveraging our strong pipeline to help increase healthcare accessibility.
Biosimilars have no clinical differentiation from existing, approved biologics, with equivalent efficacy and safety. Product demand is increasing because of:
The development and manufacture of biosimilars is a complex and challenging process.
We have invested in our biosimilar capabilities with our advanced pipeline and EnzeneXTM continuous bioprocess manufacturing, allowing us to develop, manufacture and launch a range of biosimilar products.
Originator |
Disease Indication |
Treatments |
Launch Year |
Market/Territory |
Teriparatide (Forteo®) |
Osteoporosis |
A recombinant human parathyroid hormone that acts as an anti-osteoporosis agent. Used to treat postmenopausal women and to increase bone mass in men with osteoporosis. Also used to treat men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture. |
FY21 |
India, Global |
Denosumab (Prolia®) |
Postmenopausal osteoporosis |
A human IgG2 monoclonal antibody (mAb) used to treat postmenopausal osteoporosis, fractures and bone loss in patients undergoing hormone ablation for cancer, as well as inhibition of the progression of bone erosion associated with rheumatoid arthritis. |
FY22, FY24-FY26 |
India, Global |
Denosumab (Xgeva®) |
Giant cell tumor of bone |
A human IgG2 mAb that acts as an antineoplastic agent for the prevention of skeletal-related events in patients with bone metastases from multiple myeloma and giant cell tumor of bone. |
FY22, FY24-FY26 |
India, Global |
Romiplostim (Nplate®) |
Immune thrombocytopenic purpura (ITP) |
An Fc-peptide fusion protein for treating adults and pediatrics (1+) with long-term ITP, and for treating aplastic anemia (AA) in adults with inadequate response to conventional therapy. |
FY22, FY24 |
India, Global |
Adalimumab (Humira®) |
Rheumatoid arthritis |
A human IgG1 mAb for human tumor necrosis factor (TNF). Used to reduce signs and symptoms, inhibiting the progression of structural damage and improving physical function in adult patients with moderately to severely active rheumatoid arthritis. |
FY23 |
India |
Cetuximab (Erbitux®) |
Squamous cell cancer of the head and neck |
A chimeric igG1 mAb that acts as an anti-neoplastic agent for treating patients with epidermal growth factor receptor (EGPR)-expressing, RAS wild-type metastatic colorectal cancer and for the treatment of patients with squamous cell cancer of the head and neck. |
FY24 |
India, Global |
Bevacizumab (Avastin®) |
Metastatic colorectal cancer |
A recombinant humanized IgG1 mAb used to treat metastatic colorectal cancer, non-squamous non-small cell lung cancer and glioblastoma. |
FY24 |
India, Global |
Ranibizumab (Lucentis®) |
Neovascular (Wet) age-related macular degeneration |
A humanized mAb fragment and a recombinant humanized igG1 isotype designed to bind and inhibit vascular endothelial growth factor (VEGF-A). Used for treating neovascular (Wet) age-related macular degeneration, macular edema following retinal vein occlusion (RVO), and diabetic macular edema. |
FY24 |
India |
Originator |
Disease Indication |
Treatments |
Launch Year |
Market/Territory |
Nivolumab (Opdivo®) |
Cancer of the lungs, kidneys, liver, bladder and stomach |
A humanized mAb which acts as an immune checkpoint inhibitor. Targets and blocks PD-1 protein on the surface of T-cells. |
FY26 |
India |
Omalizumab (Xolair®) |
Persistent asthma, nasal polyps and chronic spontaneous urticaria |
A humanized mAb that binds IgE. When overproduced IgE leads to an allergic response, by removing free IgE in the blood, symptoms of an allergic response are reduced. |
FY26 |
India |
Benralizumab (Fasenra®) |
Severe eosinophilic asthma |
A humanized mAb that attaches to interleukin-5 receptors on the surface of eosinophils, interfering with binding and activating an immune response. |
FY27 |
TBD |
Golimumab (Simponi®) |
Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and ulcerative colitis |
A humanized mAb that inhibits TNF-a reducing inflammation and other disease symptoms. |
FY27 |
India |
Vedolizumab (Entyvio®) |
Ulcerative colitis and Crohn’s disease |
A humanized mAb designed to bind alfa-4-beta-7 integrin, a protein found on the surface of certain white blood cells in the gut, reducing inflammation. |
FY28 |
India |
Secukinumab (Cosentyx®) |
Psoriasis, ankylosing spondylitis and psoriatic arthritis |
A humanized mAb which inhibits IL-17 in the blood. This reduces immune responses and symptoms. |
FY28 |
India |
Pembrolizumab (Keytruda®) |
Melanoma, lung cancer, head and neck cancer, Hodgkin’s lymphoma, and stomach cancer |
A humanized mAb which acts as an immune checkpoint inhibitor. Targets and blocks PD-1 and PD-L1 proteins on the surface of T-cells. |
FY29 |
Global and India |
Daratumumab (Darzalex®) |
Multiple myeloma |
A humanized mAb that binds to CD38 proteins on the surface of myeloma cells. These cells can then be killed by the immune system. |
FY29 |
India |
Natalizumab (Tysabri®) |
Relapsing forms of multiple sclerosis and Crohn's disease |
A humanized mAb that binds ɑ4-integrin present on white blood cells. This prevents autoreactive leukocytes from entering target organs and reduces inflammation. |
FY29 |
India |
Find out more about our biosimilars products and see how we can help you deliver trusted and affordable medicines at speed.